Author

T. N. Siegel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Beaver· 1 shared A. J. Kraus· 1 shared B. Bobb· 1 shared B. Cordeiro· 1 shared B. L. Weiss· 1 shared B. Zhang· 1 shared D. d. S. Pires· 1 shared E. O. Awuoche· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Beaver

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2 papers

Recent·Most cited

MicrobiologybioRxivJun 27, 2022

Extravascular spaces are the primary reservoir of antigenic diversity in Trypanosoma brucei infection

A. Beaver, Z. Keneskhanova, R. O. Cosentino…·M. R. Mugnier

The paper shows that extravascular spaces, not the bloodstream, are the main source of antigenic diversity in Trypanosoma brucei infections, with over 75% of VSGs found exclusively in these spaces.

DOI 10.1038/s41586-024-08151-z

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintJun 8, 2021

{-}{-} Histone H2B.V demarcates strategic regions in the Trypanosoma cruzi genome, associates with a bromodomain factor and affects parasite differentiation and host cell invasion

J. N. Roson, M. O. Vitarelli, H. M. Costa-Silva…·J. P. C. da Cunha

This study identifies H2B.V as a histone variant that marks strategic genomic regions in T. cruzi, interacts with regulatory proteins, and influences parasite differentiation and host cell invasion.

DOI 10.1101/2021.06.08.447515

ChIP-seqexperimental assay

𝕏 PostBluesky