Author

T. N. Tham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Dessen· 1 shared A. Lebreton· 1 shared A. Pagliuso· 1 shared A. Sartori-Rupp· 1 shared A. V. Komarova· 1 shared B. Dupuy· 1 shared C. Becavin· 1 shared C. Beloin· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Dessen

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2 papers

Recent·Most cited

An ancient divide in outer membrane tethering systems in Bacteria

J. Witwinowski, A. Sartori-Rupp, N. Taib, N. Pende, T. N. Tham, D. Poppleton, J.-M. Ghigo, C. Beloin, S. Gribaldo

The paper investigates the evolution of outer membrane tethering systems in bacteria, showing a bimodal distribution linked to phylogeny and proposing a mechanism for the loss of the outer membrane in Gram-positive bacteria.

bioRxiv · May 31, 2021 · PreprintMicrobiology

An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling

A. Pagliuso, T. N. Tham, E. Allemand, S. Robertin, B. Dupuy, Q. Bertrand, C. Becavin, M. Koutero, V. Najburg, M.-A. Nahori, F. Stavru, A. Dessen, C. Muchard, A. Lebreton, A. V. Komarova, P. Cossart

This study identifies Zea, an RNA-binding protein secreted by L. monocytogenes, which stabilizes bacterial RNAs and activates RIG-I signaling to enhance interferon β production and modulate virulence.

bioRxiv · Mar 17, 2019 · PreprintCell Biology