Author

T. O'Loughlin

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

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A. Ghannam· 1 shared A. J. Kruppa· 1 shared A. L. Ribeiro· 1 shared A. M. Smith· 1 shared F. Buss· 1 shared J. R. Edgar· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperCell Biology

A. Ghannam

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintAug 22, 2019

OPTN translocates to an ATG9A-positive compartment to regulate innate immune signalling and cytokine secretion

T. O'Loughlin, A. J. Kruppa, A. L. Ribeiro…·F. Buss

The paper shows OPTN regulates innate immune signaling by forming a perinuclear compartment with ATG9A, and disease mutations disrupt this process, affecting cytokine secretion.

DOI 10.1101/744672

humanproteomics

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