Identification of novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation
T. Wang, A. Soundararajan, J. Rabinowitz, A. Jaiswal, T. Osborne, P. P. Pattabiraman
This study identifies SREBPs as regulators of intraocular pressure by modulating TM biomechanics through lipogenesis and ECM dynamics.
bioRxiv · Feb 5, 2023Cell Biology