Author

T. R. Lambeth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Julian· 1 shared R. R. Julian· 1 shared Y. Zhang· 1 shared Z. Dai· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

R. Julian

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2 papers

Recent·Most cited

Lysosomal proteolysis of amyloid beta is impeded by fibrils grown in both acidic and neutral pH environments

T. R. Lambeth, R. R. Julian

This study shows that amyloid-beta fibrils grown in neutral or acidic pH resist lysosomal proteolysis, with neutral pH fibrils being more resistant overall.

bioRxiv · Jun 18, 2021Biochemistry

A two-trick pony: lysosomal protease cathepsin B possesses surprising ligase activity

T. R. Lambeth, Z. Dai, Y. Zhang, R. Julian

This study identifies cathepsin B as a protease with unexpected ligase activity, showing it can both cleave and join peptides through a two-step mechanism.

bioRxiv · May 7, 2020Biochemistry