Author

T. Redfern-Nichols

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. R. Harwood· 1 shared D. A. Sykes· 1 shared D. Veprintsev· 1 shared G. Ladds· 1 shared S. J. Briddon· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

C. R. Harwood

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1 paper

Recent·Most cited

Agonist efficacy at the B2AR is driven by agonist-induced differences in receptor affinity for the Gs protein, not ligand binding kinetics.

C. R. Harwood, D. A. Sykes, T. Redfern-Nichols, G. Ladds, S. J. Briddon, D. Veprintsev

This study shows that agonist efficacy at the {beta}2AR is determined by differences in receptor affinity for Gs protein, not ligand binding kinetics.

bioRxiv · Jan 5, 2024 · PreprintPharmacology & Toxicology