Clonotypic Heterogeneity In Cutaneous T-Cell Lymphoma Revealed By Comprehensive Whole Exome/Transcriptome Sequencing
A. Iyer, J. Patterson, T. Salopek, G. Ka-Shu Wong, R. Gniadecki
This study uses whole exome and transcriptome sequencing to analyze TCR clonality in mycosis fungoides, revealing multiple clonotypes in half of the samples, suggesting malignant transformation occurs at an early progenitor stage.
bioRxiv · Aug 31, 2018Cancer Biology