Pharmacokinetics of Sustained-Release Buprenorphine and Extended-Release Buprenorphine in Mice with Surgical Catheterization
M. Saenz, E. A. Bloom-Saldana, T. Synold, R. W. Ermel, P. T. Fueger, J. B. Finlay
This study compares the pharmacokinetics and therapeutic efficacy of sustained-release and extended-release buprenorphine in surgically catheterized mice, showing both maintain therapeutic concentrations for 72 hours.
bioRxiv · Mar 14, 2022Pharmacology & Toxicology