Author

T. T. Sims

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:metagenomics· 2 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

G. Biegert· 3 shared M. Ahmed-Kaddar· 3 shared T. Karpinets· 3 shared T. Solley· 3 shared X. Wu· 3 shared A. Jhingran· 2 shared A. Klopp· 2 shared J. Yue· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

G. Biegert

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Author profile →

3 papers

Recent·Most cited

Diversity and composition of gut microbiome of cervical cancer patients by 16S rRNA and whole-metagenome sequencing

G. Biegert, T. Karpinets, X. Wu, M. B. El Alam, T. T. Sims, K. Yoshida-Court, E. J. Lynn, J. Yue, A. Delgado Medrano, J. Petrosino, M. P. Mezzari, N. J. Ajami, T. Solley, M. Ahmed-Kaddar, L. E. Colbert, A. H. Klopp

This study compares 16S rRNA and whole-metagenome sequencing in cervical cancer patients, finding congruence in diversity metrics but discrepancies in genus-level abundances.

bioRxiv · May 5, 2020 · PreprintMicrobiology

Adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

M. B. El Alam, T. T. Sims, R. Kouzy, G. Biegert, J. Abi Jaoude, T. Karpinets, K. Y. Court, X. Wu, A. D. Medrano, M. Mezzari, N. Ajami, T. Solley, M. Ahmed-Kaddar, L. Lin, L. Ramondetta, , L. Colbert

This study tracks gut microbiome diversity and composition changes in gynecologic cancer patients undergoing chemoradiotherapy, finding reduced diversity during treatment but partial recovery by week 12.

bioRxiv · Apr 10, 2020Cancer Biology

Dynamic evolution of cervical cancer mutations during chemoradiation using novel sampling approach

B. V. Chapman, T. Karpinets, T. T. Sims, G. Biegert, X. Wu, A. Y. Delgado Medrano, P. J. Eifel, A. Jhingran, L. L. Lin, L. M. Ramondetta, A. M. Futreal, A. A. Jazaeri, M. Frumovitz, K. M. Schmeler, J. Yue, , L. Colbert

This study uses whole exome sequencing to track cervical cancer mutations during chemoradiation, finding that CDK4/CDK6/cyclin D1-related mutations persist or increase, suggesting radiation resistance.

bioRxiv · Nov 25, 2019 · PreprintCancer Biology