Dynamic evolution of cervical cancer mutations during chemoradiation using novel sampling approach
B. V. Chapman, T. Karpinets, T. T. Sims, G. Biegert, X. Wu, A. Y. Delgado Medrano, P. J. Eifel, A. Jhingran, L. L. Lin, L. M. Ramondetta, A. M. Futreal, A. A. Jazaeri, M. Frumovitz, K. M. Schmeler, J. Yue, , L. Colbert
This study uses whole exome sequencing to track cervical cancer mutations during chemoradiation, finding that CDK4/CDK6/cyclin D1-related mutations persist or increase, suggesting radiation resistance.
bioRxiv · Nov 25, 2019 · PreprintCancer Biology