Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A
R. Cacioppo, H. B. Akman, T. Tuncer, A. E. Erson-Bensan, C. Lindon
The paper identifies that differential translation of AURKA mRNA isoforms, regulated by miRNA and alternative polyadenylation, contributes to oncogenic activation of Aurora A in breast cancer.
bioRxiv · Mar 13, 2023Cell Biology