Author

H. B. Akman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Lindon· 3 shared G. Guarguaglini· 2 shared R. Grant· 2 shared A. A. Abdelbaki· 1 shared A. Abdelbaki· 1 shared A. E. Erson-Bensan· 1 shared A. Hagting· 1 shared A. Paiardini· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

C. Lindon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A

R. Cacioppo, H. B. Akman, T. Tuncer, A. E. Erson-Bensan, C. Lindon

The paper identifies that differential translation of AURKA mRNA isoforms, regulated by miRNA and alternative polyadenylation, contributes to oncogenic activation of Aurora A in breast cancer.

bioRxiv · Mar 13, 2023Cell Biology

Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1

C. Lindon, A. A. Abdelbaki, C. Ascanelli, C. Okoye, H. B. Akman, G. Janson, M.-w. Min, C. Marcozzi, A. Hagting, R. Grant, M. De Luca, I. A. Asteriti, G. Guarguaglini, A. Paiardini

This study redefines AURKA degron motifs, showing the N-terminal A-box functions as a D-box and the C-terminal D-box is not a degron but a structural motif essential for AURKA's active conformation.

bioRxiv · Jan 31, 2022Cell Biology

AURKA destruction is decoupled from its activity at mitotic exit but suppresses interphase activity

A. Abdelbaki, H. B. Akman, M. Poteau, R. Grant, G. Guarguaglini, o. C. G. Gavet, C. Lindon

The paper investigates AURKA activity regulation, finding that its inactivation at mitotic exit depends on TPX2 degradation, not AURKA destruction, and that FZR1 suppresses interphase AURKA activity.

bioRxiv · Nov 21, 2019Cell Biology