The in situ structure of Parkinson’s disease-linked LRRK2
R. Watanabe, R. Buschauer, J. Boehning, M. Audagnotto, K. Lasker, T. W. Lu, D. Boassa, S. Taylor, E. Villa
This study uses cryo-electron tomography to reveal the in situ structure of LRRK2 with a pathogenic mutation, showing its oligomerization around microtubules and functional domains.
bioRxiv · Nov 10, 2019Biophysics