R. Watanabe

Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis

This study shows that downregulation of Sema4A in keratinocytes is associated with non-lesional psoriasis features and that Sema4A regulates skin homeostasis and inflammation.

Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.

This study uses cryo-electron tomography to reveal the structure of the intracellular Ebola virus nucleocapsid, identifying a new outer layer of NP complexed with VP35 and conserved assembly interfaces.

The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2

The paper presents the cryo-EM structure of the chicken CENP-A nucleosome complexed with ggKNL2, revealing how ggKNL2 recognizes CENP-A and facilitates its deposition.

Particle morphology of medusavirus inside and outside the cells reveals a new maturation process of giant viruses

The paper investigates medusavirus morphology and maturation using electron microscopy, revealing a new maturation process with distinct particle types and structural features.

Parkinson's Disease-linked LRRK2 structure and model for microtubule interaction

This study reports the structure of LRRK2 and its interaction with microtubules, showing that its conformation regulates binding and affects motor protein function.

The in situ structure of Parkinson’s disease-linked LRRK2

This study uses cryo-electron tomography to reveal the in situ structure of LRRK2 with a pathogenic mutation, showing its oligomerization around microtubules and functional domains.

The molecular architecture of engulfment during Bacillus subtilis sporulation

This study uses cryo-electron tomography to visualize Bacillus subtilis sporulation, revealing new insights into the engulfment process and the role of the SpoIIDMP complex in membrane migration.