J. Boehning

Structure of the Pseudomonas aeruginosa PAO1 Type IV pilus

This study reports the 3.2 Å resolution structure of the Pseudomonas aeruginosa PAO1 Type IV pilus using cryo-EM, revealing its architecture and potential functional roles.

Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar

The paper uses cryo-EM to determine the gas-phase structure of β-galactosidase at 2.6 Å resolution, showing structural similarity to its native state.

Biophysical basis of phage liquid crystalline droplet-mediated antibiotic tolerance in pathogenic bacteria

This study investigates liquid crystalline droplets formed by inoviral phages in bacteria, showing they protect cells from antibiotics through biophysical properties rather than surface chemistry.

Architecture of the biofilm-associated archaic CupE pilus from Pseudomonas aeruginosa

This study presents the structure of the archaic CupE pilus from Pseudomonas aeruginosa, revealing its zigzag architecture and role in biofilm formation.

Molecular architecture of the TasA biofilm scaffold in Bacillus subtilis

This study reveals the molecular structure of TasA biofilm scaffolds in Bacillus subtilis, showing they form β-sheet-rich filaments through donor strand complementation, essential for biofilm formation.

Architecture of cell-cell junctions in situ reveals a mechanism for bacterial biofilm inhibition

The paper reveals the structure and function of CdrA in Pseudomonas aeruginosa biofilms, showing how it mediates cell-cell interactions and how targeting it can inhibit biofilm formation.

The in situ structure of Parkinson’s disease-linked LRRK2

This study uses cryo-electron tomography to reveal the in situ structure of LRRK2 with a pathogenic mutation, showing its oligomerization around microtubules and functional domains.