Discovery and Validation of Alternatives to VSV-G for Pseudotyping of Lentiviral Vectors for In Vivo Delivery of Anti-Tumor Transgenes
Matthew J. Spindler, Alyssa Amezquita, Eamon F.X. Byrne, R. C. Edgar, S. S. Ravi, Savreet K. Sandhu, T. Weller, David S. Johnson
The paper identifies and validates an alternative to VSV-G for lentivector pseudotyping to improve in vivo T cell transgene delivery for tumor therapy.
bioRxiv · Mar 3, 2025 · PreprintCancer Biology