EZH2/ hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression
Z.-S. Lin, C.-C. Chung, Y.-C. Liu, C.-H. Chang, H.-C. Liu, Y.-Y. Liang, T.-L. Huang, T.-M. Chen, C.-H. Lee, C.-H. Tang, Y.-H. Chen, M.-C. Hung
This study identifies the EZH2/SULF1/cMET axis as a driver of chondrosarcoma progression and shows that targeting this pathway can slow tumor growth and improve survival in mouse models.
bioRxiv · Jun 7, 2022Cancer Biology