Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes
K. O. Brandao, V. Meraviglia, D. Salvatori, X. Cao, L. P. Sala, L. Yiangou, M. P. H. Mol, M. Bellin, C. L. Mummery, R. P. Davis
The paper shows that a gain of chromosome 1q31.3 in human iPSCs leads to increased TNNT2 expression and altered contraction in derived cardiomyocytes.
bioRxiv · Dec 11, 2023 · PreprintCell Biology