Individual Host Variation in Single-cell Responses to Enteroaggregative Escherichia coli Infection Modeled with Human Colon Organoids
Ling Qiu, Tajhal D. Patel, Hannah E. Jones, Cristian Coarfa, Anthony William Maresso
This study uses single-cell RNA sequencing on human colon organoids to show donor-specific responses to EAEC infection, revealing host-driven disease heterogeneity at the single-cell level.
mSphere · Aug 11, 2026Peer-reviewedMicrobiology