Anthony William Maresso

EsViritu is a viral pathogen profiler that accurately detects and reconstructs virus genomes from metagenomes with high sensitivity and specificity.

This study amplifies and sequences human antibody VDJ regions from wastewater, showing diverse antibody sequences and potential for population immunity analysis.

This study uses single-cell RNA sequencing on human colon organoids to show donor-specific responses to EAEC infection, revealing host-driven disease heterogeneity at the single-cell level.

This paper develops a method to discover virulent phages against antibiotic-resistant pathogens by combining environmental sampling, 16S rRNA sequencing, and a portable device for phage enrichment.

This study shows that bacteriophages can reduce uropathogenic E. coli (UPEC) colonization in vitro and in a mouse model, suggesting phage therapy as a potential UTI prevention strategy.

This study examines cytokine and immunoglobulin responses in nine patients undergoing intravenous phage therapy, finding heterogeneous cytokine patterns and IgM responses that vary with immune status and pathogen.

Strainify estimates strain-level abundances from low-coverage short-read metagenomic data, outperforming existing methods in simulated and real datasets.

This study develops human bladder organoids to model UTIs and phage therapy, showing phage reduces bacterial loads and inflammation during infection.

This paper identifies biochemical enhancers of PET biodegradation by Piscinibacter sakaiensis using iterative screening and biodegradation assays.

This study identifies major sources of transcriptomic variation in human intestinal organoids, showing that culture methods like substrate and format have large effects compared to experimental manipulations.