Helical charge distribution at the transmembrane-luminal interface determines subcellular localization
Haddas Saad, Ron Benyair, Tal Mazor, Gerardo Zelmar Lederkremer
The paper identifies a conserved helical charge pattern in the luminal juxtamembrane region of Class I mannosidases that determines their subcellular localization between quality control vesicles and the Golgi.
bioRxiv · Nov 12, 2025 · PreprintCell Biology