Author

Tamotsu Noguchi

Meiji Pharmaceutical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Hiroto AnboiD· 1 shared Keiichi HommaiD· 1 shared Keiichi IzumikawaiD· 1 shared Maiko Nagai· 1 shared Masami NagahamaiD· 1 shared Minoru SugiharaiD· 1 shared Ryosuke Kamimura· 1 shared Satoshi FukuchiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Hiroto AnboORCID

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2 papers

Recent·Most cited

Molecular basis of the autoregulatory mechanism of motor neuron-related splicing factor 30

Keiichi Izumikawa, Tatsuya Shida, Yuuka Onodera, Yuito Tashima, Sotaro Miyao, Tomomi Suda, Yasuyuki Suda, Ryosuke Kamimura, Maiko Nagai, Minoru Sugihara, Tamotsu Noguchi, Masami Nagahama

This study identifies the molecular mechanism by which SPF30 autoregulates its expression through alternative splicing and nonsense-mediated decay.

Journal of Biological Chemistry · Jul 25, 2025Peer-reviewedMolecular Biology

Exon Elongation Added Intrinsically Disordered Regions to the Encoded Proteins and Facilitated the Emergence of the Last Eukaryotic Common Ancestor

Satoshi Fukuchi, Tamotsu Noguchi, Hiroto Anbo, Keiichi Homma

The paper proposes a model for the evolution of eukaryotic proteins from prokaryotic ones, linking exon elongation to the emergence of intrinsically disordered regions and multiple structural domains.

Molecular Biology and Evolution · Dec 16, 2022Peer-reviewedBioinformatics