Isoquercetin treatment of mouse sickled red blood cells shows a discernible deformability and sickling phenotype
Osamede C. Owegie, Iván Hancco Zirena, Tanvi Penubothu, Ionita Calin Ghiran, Moua Yang
This study investigates the effects of isoquercetin on sickled red blood cells in mice, showing increased elongation and dehydration when thiol isomerases are antagonized.
bioRxiv · Apr 28, 2026 · PreprintPharmacology & Toxicology