Osamede C. Owegie

This paper shows punicalagin inhibits both oxidase and reductase activities of PDI through noncovalent, allosteric binding at the N-terminal domain and identifies PDI as a high-confidence target of galloylated polyphenols.

This study investigates the effects of isoquercetin on sickled red blood cells in mice, showing increased elongation and dehydration when thiol isomerases are antagonized.