BioinformaticsbioRxivPreprint
Random forest classifiers trained on simulated data enable accurate short read-based genotyping of structural variants in the alpha globin region at Chr16p13.3
Nancy Fisher Hansen, Xunde Wang, Mickias B. Tegegn…·James C. Mullikin
The paper uses random forest classifiers trained on simulated data to accurately genotype structural variants in the alpha globin region, outperforming existing software in ancestry-specific allele frequency estimation.