Mateus Henrique Gouveia

The paper identifies non-random positional overlap between common germline polymorphisms and somatic cancer mutations, suggesting intrinsically vulnerable genomic loci.

The paper identifies a novel genetic locus OSBPL11 associated with vitamin D levels and cardiometabolic health in African populations through genome-wide analysis.

The paper analyzes genome-wide data from 432 Peruvian urban individuals to reveal fine-scale population structure, admixture dynamics, and demographic patterns shaped by ancient and recent events.

The paper analyzes genetic diversity in the All of Us Research Program, showing that self-identified race and ethnicity groups exhibit continuous genetic variation rather than discrete clusters, with implications for genetic association studies.

The paper uses random forest classifiers trained on simulated data to accurately genotype structural variants in the alpha globin region, outperforming existing software in ancestry-specific allele frequency estimation.

The paper conducts an X-chromosome association study in Latin American cohorts, identifying new loci linked to Parkinson Disease and replicating previous findings.

NATO RA prunes relatedness in genetic datasets to minimize data loss, outperforming existing methods by retaining more individuals while removing all relatives.

This paper conducts a GWAS in Africans to identify novel lipid loci and finds 23 novel associations, with some replicating in African Americans and additional loci emerging from meta-analysis.

The paper identifies a West African-associated regulatory variant with a strong female-specific effect on BMI and fat mass in Brazilian admixed populations.

The paper analyzes African genetic contributions to the Americas, showing regional ancestry patterns and admixture dynamics linked to historical factors.