Cancer BiologybioRxivPreprint
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai…·Rebekka K. Schneider
This study identifies Spp1⁺ macrophages as key hubs coordinating fibrotic remodeling in myeloproliferative neoplasms using NicheSphere, a novel computational method for cell communication analysis.