Hmgb1 release kinetics shape its extracellular functions during regulated cell death
Shin Murai, Da Young Shin, Kenta Sumiyama, Kenta Moriwaki, Akira Muto, Kanako Takakura, Mai Yamagishi, Yoshitaka Shirasaki, Takumi Kanokogi, Sachiko Komazawa‐Sakon, Tetuo Mikami, Masahiro Nishibori, Katsuhide Okunishi, Kenta Terai, Hiroyasu Nakano
The paper investigates Hmgb1 release kinetics during regulated cell death and shows that rapid release generates higher local concentrations, influencing its extracellular functions.
bioRxiv · May 17, 2026 · PreprintCell Biology