Author

Yoshitaka Shirasaki

Research Center for Advanced Science and Technology, The University of TokyoORCID 0000-0002-3808-1630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Akira MutoiD· 1 shared Da Young Shin· 1 shared Hiroyasu NakanoiD· 1 shared Kanako Takakura· 1 shared Katsuhide OkunishiiD· 1 shared Katsumori SegawaiD· 1 shared Kenta MoriwakiiD· 1 shared Kenta SumiyamaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Akira MutoORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 17, 2026

Hmgb1 release kinetics shape its extracellular functions during regulated cell death

Shin Murai, Da Young Shin, Kenta Sumiyama…·Hiroyasu Nakano

The paper investigates Hmgb1 release kinetics during regulated cell death and shows that rapid release generates higher local concentrations, influencing its extracellular functions.

DOI 10.64898/2026.05.15.725293

mouseimaging

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Cell BiologybioRxivPreprintMar 17, 2025

Early-peaking caspase-7 activity at the plasma membrane drives apoptotic phosphatidylserine exposure

Yusuke Taira, Zhuohao Yang, Yugo Miyata…·Natsuki Shinoda

This study identifies caspase-7 as responsible for early-peaking caspase activity at the plasma membrane during apoptosis, which drives phosphatidylserine exposure and efferocytosis.

3 citations

humanproteomics

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