Developing Biosensors for Specific Assessment of Trans-translation in Pseudomonas aeruginosa.
Bastien L’Hermitte, Thomas Chauvet, Sylvie Georgeault, Nicolas Le Yondre, Philippe Jéhan, Reynald Gillet, Christine Baysse
The paper develops two biosensors in Pseudomonas aeruginosa to detect trans-translation inhibitors, validated through gene deletions and complementation, and demonstrates their use in screening antibiotics and inhibitors.
ACS Synthetic Biology · Mar 6, 2025Peer-reviewedMicrobiology