Author

Reynald Gillet

Centre National de la Recherche ScientifiqueORCID 0000-0001-9458-9503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Sylvie GeorgeaultiD· 2 shared Bastien L’HermitteiD· 1 shared Christine BaysseiD· 1 shared Emmanuel GiudiceiD· 1 shared Mohamed SassiiD· 1 shared Nicolas Le YondreiD· 1 shared Olivier DelalandeiD· 1 shared Philippe Jéhan· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Sylvie GeorgeaultORCID

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2 papers

Recent·Most cited

Structural characterization of hibernating ribosomes in four Gram-negative pathogenic bacteria

Radhakrishnan B. Vasanthakrishnan, Olivier Delalande, Yann Lefrancois Copy, Sophie Chat, Sylvie Georgeault, Mohamed Sassi, Emmanuel Giudice, Reynald Gillet

This study reports cryo-EM structures of hibernating ribosomes from four Gram-negative bacteria, revealing how hibernation factors inhibit translation.

Communications Biology · Sep 24, 2026Peer-reviewedBiochemistry

Developing Biosensors for Specific Assessment of Trans-translation in Pseudomonas aeruginosa.

Bastien L’Hermitte, Thomas Chauvet, Sylvie Georgeault, Nicolas Le Yondre, Philippe Jéhan, Reynald Gillet, Christine Baysse

The paper develops two biosensors in Pseudomonas aeruginosa to detect trans-translation inhibitors, validated through gene deletions and complementation, and demonstrates their use in screening antibiotics and inhibitors.

ACS Synthetic Biology · Mar 6, 2025Peer-reviewedMicrobiology