Author

Thomas Christian

Thomas Jefferson University

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Cell Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

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Douglas C. WallaceiD· 1 shared Erin L. SeifertiD· 1 shared Howard GamperiD· 1 shared Joseph A. PiccirilliiD· 1 shared Meni WanunuiD· 1 shared Nan‐Sheng LiiD· 1 shared Robert Y. HenleyiD· 1 shared Sunita MaharjaniD· 1 shared

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1 shared paperCell Biology

Douglas C. WallaceORCID

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1 paper

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedOct 18, 2024

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology

Sunita Maharjan, Howard Gamper, Yuka Yamaki…·Ya‐Ming Hou

The paper shows that N1-methylation at position 9 of mt-Leu(UAA) stabilizes wild-type mt-tRNA but destabilizes pathogenic variants, suggesting methylation control could be therapeutic.

6 citations

humanexperimental assay

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