Author

Thomas Cowart

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro BarreraiD· 1 shared Alexander C. Nelson· 1 shared Andrew S. AlleniD· 1 shared Charles A. GersbachiD· 1 shared Gregory E. CrawfordiD· 1 shared Julia W. RileyiD· 1 shared Lexi R. BoundsiD· 1 shared Marisa C. HamiltoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alejandro BarreraORCID

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1 paper

Recent·Most cited

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER

Siyan Liu, Marisa C. Hamilton, Thomas Cowart, Alejandro Barrera, Lexi R. Bounds, Alexander C. Nelson, Sophie F. Dornbaum, Julia W. Riley, Richard W. Doty, Andrew S. Allen, Gregory E. Crawford, William H. Majoros, Charles A. Gersbach

The paper develops CLEANSER, a model to filter ambient gRNAs in single-cell CRISPR screens, improving gRNA-cell assignment accuracy and differential gene expression analysis.

Cell Genomics · Feb 1, 2025Peer-reviewedGenomics