GenomicsCell GenomicsPeer-reviewed
Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER
Siyan Liu, Marisa C. Hamilton, Thomas Cowart…·Charles A. Gersbach
The paper develops CLEANSER, a model to filter ambient gRNAs in single-cell CRISPR screens, improving gRNA-cell assignment accuracy and differential gene expression analysis.
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