Mutual Inhibition Model of pattern formation: The role of Wnt-Dickkopf interactions in driving Hydra body axis formation
Moritz Mercker, Alexey Kazarnikov, Anja Tursch, Thomas Richter, Suat Özbek, Thomas Holstein, Anna K. Marciniak-Czochra
The paper introduces a mathematical model of Wnt-Dickkopf interactions in Hydra to explain body-axis formation through mutual inhibition, showing it can drive pattern formation across a broad parameter range.
PLoS Computational Biology · Jul 13, 2026Peer-reviewedDevelopmental Biology