Anja Tursch

Mutual Inhibition Model of pattern formation: The role of Wnt-Dickkopf interactions in driving Hydra body axis formation

The paper introduces a mathematical model of Wnt-Dickkopf interactions in Hydra to explain body-axis formation through mutual inhibition, showing it can drive pattern formation across a broad parameter range.

Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast

This study identifies Tsa1 as the primary peroxide scavenger in yeast and shows it can generate GSSG under H2O2 conditions.

Two interconnected patterning loops are required for body axis and head organizer formation in Hydra

This study shows that Hydra uses two separate patterning loops for body axis and head formation, challenging the previous single-loop model.

MAPK signaling links the injury response to Wnt-regulated patterning in Hydra regeneration

This study identifies MAPK signaling as a critical pathway linking injury response to Wnt-regulated patterning in Hydra regeneration.

Genetic knockdown and knockout approaches in Hydra

This study develops CRISPR-Cas9 and siRNA delivery methods for genetic manipulation in Hydra, enabling reliable gene interference and functional studies.