Nature of epigenetic aging from a single-cell perspective
Andrei E. Tarkhov, Thomas Lindstrom-Vautrin, Sirui Zhang, Kejun Ying, Mahdi Moqri, Bohan Zhang, Alexander Tyshkovskiy, Orr Levy, Vadim N. Gladyshev
The paper investigates epigenetic aging by comparing single-cell DNA methylation changes across aging and development, revealing stochastic patterns and introducing a new algorithm for analyzing CpG clusters.
Nature Aging · May 9, 2024Peer-reviewedSystems Biology