Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Michela Menegollo, Robert B. Bentham, Tiago Henriques, Seow Q. Ng, Ziyu Ren, Clarinde Esculier, Sia Agarwal, Emily T.Y. Tong, Clement Lo, Sanjana Ilangovan, Zorka Szabadkai, Matteo Suman, Neill Patani, Avinash D. Ghanate, Kevin Bryson, , György Szabadkai
The paper introduces a method to identify metabolic switches in breast cancer transcriptomes, revealing gene clusters associated with mitochondrial and metabolic states and their clinical implications.
bioRxiv · Feb 17, 2023 · PreprintSystems Biology