Ziyu Ren

Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer

The paper introduces a method to identify metabolic switches in breast cancer transcriptomes, revealing gene clusters associated with mitochondrial and metabolic states and their clinical implications.

A family of transcription factors that limit lifespan: ETS factors have conserved roles in longevity

This study identifies ETS transcription factors as conserved regulators of longevity across species, showing their roles in modulating lifespan through gene expression programs.

Monsters in the uterus: A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

The paper investigates uterine tumors in C. elegans as a senescent pathology caused by quasi-programs, showing similarities to teratomas and senescence.