Author
University College LondonORCID 0000-0002-3006-3577Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kritarth Singh, Hormos Salimi Dafsari, Olivia Gillham…·Michael R. Duchen
This study identifies EPG5 mutations causing neurodegeneration via mitochondrial dysfunction and innate immune activation in patient-derived cells.
In-Won Lee, Morteza Nazari, Jazmine Yuson…·John Carroll
The paper identifies mechanisms of mitochondrial streaming in oocytes, showing actin-driven and chromatin-associated pathways that pattern mitochondrial distribution.
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher…·Michael R. Duchen
This study identifies redox-dependent binding configurations of NAD(P)H in live cells using FLIM and modeling, revealing how redox states influence fluorescence decay.
Michela Menegollo, Robert B. Bentham, Tiago Henriques…·György Szabadkai
The paper introduces a method to identify metabolic switches in breast cancer transcriptomes, revealing gene clusters associated with mitochondrial and metabolic states and their clinical implications.