A sequence-based proactive intelligence for influenza antigenic profiling improves vaccine strain selection
Yihao Chen, Ying Xu, Yanhui Cheng, Xianzhi Qi, Tian Bai, Jie Yang, Huanle Luo, Xiangjun Du, L C Zhu, L S Yang, Mǎng Shī, Dayan Wang, Zhaorong Li, Yuelong Shu
This paper introduces fluProfiler, a framework using viral sequences to predict antigenic relationships and improve vaccine strain selection by reducing reliance on time-consuming HI assays.
bioRxiv · Apr 21, 2026 · PreprintBioinformatics