Yihao Chen

This paper introduces fluProfiler, a framework using viral sequences to predict antigenic relationships and improve vaccine strain selection by reducing reliance on time-consuming HI assays.

This paper introduces LucaOne, a foundation model trained on nucleic acid and protein sequences, demonstrating understanding of biological principles and performing well on related tasks.

This study identifies lipid droplet formation in microglia as a mechanism linking amyloid-beta exposure to impaired phagocytosis in Alzheimer's disease, with DGAT2 as a therapeutic target.