A genome-wide CRISPR Screening identifies targets that drive Tolerogenic Dendritic Cells
Xiaoguang Li, Liang Chen, Tiankai Han, Megha Suresh, Fedik Rahimov, Chao Gao, Jing Wang, Renze Ma, Joshua D. Stender, Kanstantsin V. Katlinski
This study uses CRISPR screening to identify molecular targets that drive the function of tolerogenic dendritic cells, revealing CD86 and UBE2L6 as key regulators of immune tolerance.
bioRxiv · Mar 25, 2026 · PreprintImmunology