STING agonists drive recruitment and intrinsic type I interferon responses in monocytic lineage cells for optimal anti-tumor immunity
Mélanie Girard, Tianning Yu, Nathália Vieira Batista, Karen K M Yeung, Sara Lamorte, Wenting Gao, Miaoxi Liu, Tracy L. McGaha, Tania H. Watts
This study shows STING agonists enhance anti-tumor immunity by recruiting monocytic cells and inducing IFN-I responses, with IL-18 playing a key role in CD8 T cell activation.
The Journal of Immunology · Jul 9, 2025Peer-reviewedImmunology