ImmunologybioRxivPreprint
Functional Type I and Type II interferon crosstalk restricts progenitor exhausted CD8 T cells through spatial exclusion and checkpoint enforcement
S. Liu, Heidi J. Elsaesser, René Vielman Quevedo…·David G. Brooks
This study identifies a spatially encoded interferon circuit that restricts progenitor exhausted CD8 T cells during chronic infection by enforcing niche sequestration and checkpoint control.