DEER of Singly Labelled Proteins to Evaluate Supramolecular Packing of Amyloid Fibrils
Karen Tsay, Asif Equbal, Yuanxin Li, Tiffany Tsui, Songi Han, Yann Fichou
This study introduces DEER spectroscopy to analyze the supramolecular packing of amyloid fibrils, showing that heparin-induced fibrils are mispacked while seeded aggregation improves packing order.
bioRxiv · Nov 10, 2025 · PreprintBiophysics