Author

Yann Fichou

Centre National de la Recherche ScientifiqueORCID 0000-0002-6520-0041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Karen TsayiD· 2 shared Madhur SrivastavaiD· 2 shared Songi HaniD· 2 shared Asif EqubaliD· 1 shared Baptiste FischeriD· 1 shared Clara PierssoniD· 1 shared Jack H. FreediD· 1 shared Melanie RossottiiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Karen TsayORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DEER of Singly Labelled Proteins to Evaluate Supramolecular Packing of Amyloid Fibrils

Karen Tsay, Asif Equbal, Yuanxin Li, Tiffany Tsui, Songi Han, Yann Fichou

This study introduces DEER spectroscopy to analyze the supramolecular packing of amyloid fibrils, showing that heparin-induced fibrils are mispacked while seeded aggregation improves packing order.

bioRxiv · Nov 10, 2025 · PreprintBiophysics

Development of an EPR-based methodology to study protein-lipid interaction

Clara Piersson, Shikhar Prakash, Victoria Lublin, Melanie Rossotti, Baptiste Fischer, Madhur Srivastava, Yann Fichou

This paper develops an EPR-based method to quantify protein-lipid interactions, demonstrating its ability to measure binding affinity and concentration of Tau protein with lipids.

Biophysical Chemistry · Nov 8, 2025Peer-reviewedBiophysics

Localized Reconstruction of Multimodal Distance Distribution from DEER Data of Biopolymers

Karen Tsay, Timothy J. Keller, Yann Fichou, Jack H. Freed, Songi Han, Madhur Srivastava

This paper introduces SF-SVD and WavPDS methods to accurately reconstruct distance distributions from DEER data of biopolymers, resolving broad and mixed features without prior knowledge.

bioRxiv · Jan 2, 2025 · PreprintBiophysics