Illuminating Dark Proteins using Reactome Pathways
Timothy Brunson, Nasim Sanati, Lisa R. Matthews, Robin Haw, Deidre Beavers, Solomon I. Shorser, Cristoffer Sevilla, Guilherme Viteri, Patrick Conley, Karen Rothfels, Henning Hermjakob, Lincoln David Stein, Peter D’Eustachio, Guanming Wu
The paper predicts functional interactions of dark proteins with Reactome pathways using a random forest classifier and develops a web portal to visualize these interactions.
bioRxiv · Jun 5, 2023 · PreprintBioinformatics