Cardiomyocyte Perm1 sustains cardiac bioenergetic reserve and exercise capacity
Shizuko Tachibana, Tina Le, Simon Schenk, Wei Feng, Ju Chen, Robert S. Ross, Stephan Lange, Yoshitake Cho
This study shows that Perm1 in cardiomyocytes is essential for maintaining cardiac bioenergetic reserve, affecting exercise capacity but not resting function.
bioRxiv · Oct 10, 2026 · PreprintPhysiology