Fetal manipulation of maternal metabolism is a critical function of Igf2 imprinting
Jorge López‐Tello, Hannah E. J. Yong, Ionel Sandovici, Efthimia R. Christoforou, Esteban Salazar‐Petres, Rebecca Boyland, Tina Napso, Miguel Constância, Amanda Nancy Sferruzzi-Perri
This study shows that Igf2 imprinting in mouse placental endocrine cells is critical for fetal manipulation of maternal metabolism, leading to nutrient allocation and offspring metabolic health outcomes.
bioRxiv · Apr 19, 2023 · PreprintDevelopmental Biology